Cholinergic Enhancement Reduces Spatial Spread of Visual Responses in Human Early Visual Cortex

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Cholinergic Enhancement Reduces Spatial Spread of Visual Responses in Human Early Visual Cortex

Animal studies have shown that acetylcholine decreases excitatory receptive field size and spread of excitation in early visual cortex. These effects are thought to be due to facilitation of thalamocortical synaptic transmission and/or suppression of intracortical connections. We have used functional magnetic resonance imaging (fMRI) to measure the spatial spread of responses to visual stimulat...

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ژورنال

عنوان ژورنال: Neuron

سال: 2008

ISSN: 0896-6273

DOI: 10.1016/j.neuron.2008.09.038